When I install Sublime Text in Linux, I report the message NOTADIRECTORYERROR: [ERRNO 20] NOT A DIRECTORY. At first I thought it was because the Defalut folder was missing, but later I realized it wasn't. I then checked the Settings of my SublimeREPL. Sublime-setings and deleted the contents after bin, and found that the program worked fine.
old: "default_extend_env": {"PATH": "{PATH}:/home/bgnv5/anaconda3/bin/python"},
new: "default_extend_env": {"PATH": "{PATH}:/home/bgnv5/anaconda3/bin/"},
Spent a lot of time to find problems, I hope to help you.